Table 1.

Efficace Criteria Checklist for Evaluating HRQOL¹⁰

HRQOL Topic	Answer
Conceptual
A priori hypothesis stated	Yes	No	N/A*
Rational for instrument reported	Yes	No
Measurement
Psychometric properties reported	Yes	No	N/A†
Cultural validity verified	Yes	No
Adequacy of domains covered	Yes	No
Methodology
Instrument administration reported	Yes	No
Baseline compliance reported	Yes	No
Timing of assessments documented	Yes	No
Missing data documented	Yes	No
Interpretation
Clinical significance addressed	Yes	No
Presentation of results in general	Yes	No

^*If a study explicitly states an exploratory HRQOL evaluation; ^†If the HRQOL measure is validated in the same population as the one of the trial.