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Motor Neuron Disease Genes Involved in RNP formation
| Gene | RNA processing pathway |
|---|---|
| SMN | UsnRNP assembly, RNP assembly |
| SETX | Transcription, processing |
| TDP-43 | Splicing |
| FUS | Splicing |
| GLE1 | mRNA transport |
| IGHMBP2 | Translation |
| GARS/YARS | Amino-acyl tRNA assembly |
| HSPB1 | AU-rich element mediated mRNA decay |
