TABLE I.

Cytokine Concentration of Pre-Inoculated and Retrieved Human Metastatic Breast Cancer Cell Variants

Cytokine concentration (ng/ml)	MDA-231W-GFP Pre	MDA-231W-GFP Post	MDA-231PY-GFP Pre	MDA-231PY-GFP Post	MDA-231BO-GFP Pre	MDA-231BO-GFP Post	MDA-231BRMS-GFP Pre	MDA-231BRMS-GFP Post
Human metastatic breast cancer cell variant type
IL-6	1.5 (1.5, 1.5)	0.7 (0.7, 0.7)	0.2 (0.2, 0.2)	0.09 (0.03, 0.3)	0.4 (0.4, 0.4)	0.09 (0.05, 0.2)	0.9 (0.9, 0.9)	Did not grow
GRO-a	3.5 (3.5, 3.5)	0.5 (0.5, 0.5)	0.3 (0.3, 0.3)	0.4 (0.4, 0.4)	1.7 (1.7, 1.7)	0.4 (0.3, 0.6)	2.4 (2.4, 2.4)	Did not grow
MCP-1	0.04 (0.04, 0.04)	0.02 (0.02, 0.02)	0.06 (0.06, 0.06)	0.04 (0, 0.09)	0.05 (0.05, 0.05)	0.03 (0.03, 0.03)	0.02 (0.02, 0.02)	Did not grow
IL-8	2.3 (2.3, 2.3)	0.6 (0.6, 0.6)	0.5 (0.5, 0.5)	0.5 (0.3, 0.8)	2.6 (2.6, 2.6)	0.8 (0.4, 1.9)	2.3 (2.3, 2.3)	Did not grow
VEGF	13.0 (13.0, 13.0)	7.9 (7.9, 7.9)	13.0 (13.0, 13.0)	9.9 (5.9, 16.0)	27.0 (27.0, 27.0)	9.0 (8.3, 9.8)	9.8 (9.8, 9.8)	Did not grow

The cytokine concentration of pre-inoculated and retrieved human metastatic breast cancer cell variants was determined using a Bio-Rad Bio-Plex^™ human cytokine array. Geometric mean (geometric mean −1 SD, geometric mean +1 SD), values were rounded to the nearest integer. Compilation of cells from at least two mice per region. No significant differences were found (P > 0.05)