. Author manuscript; available in PMC: 2014 Mar 1.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2013 Jan 25;0(2):10.1002/ajmg.b.32133. doi: 10.1002/ajmg.b.32133

TABLE II.

Estimated Parameters for QTL Models with APOE Adjustment

Analysis	Chromosome	Region (cM)	Model	P_a ^*	Heterozygote effect	Homozygote effect
Segregation Analysis	NA	NA	1	0.69 (0.12)	−7.08 (2.90)	26.36 (9.20)
Segregation Analysis	NA	NA	2	0.17 (0.11)	21.34 (4.54)	23.85 (4.13)
Joint linkage and segregation Analysis	6q16.3	100 – 125	1	0.69 (0.07)	−6.93 (2.17)	27.71 (8.53)
	11p13	25 – 90	2	0.21 (0.11)	17.89 (4.71)	21.91 (4.69)
	15q12	0 – 23	2	0.2 (0.08)	18.53 (3.53)	22.09 (4.14)
	15q14	23 – 70	2	0.18 (0.05)	21.27 (3.46)	23.47 (3.25)
	19p13.12	15 – 60	2	0.17 (0.08)	19.55 (3.68)	25.26 (4.14)
	19q13.42	65 – 80	2	0.17 (0.10)	21.09 (3.80)	24.04 (4.01)

Allele frequency of allele a. Posterior mean and sd are shown; same format for heterozygote effect and homozygote effect