Introduction to structural DNA nanotechnology. (A) Self-assembly of nanostructures based on complementary DNA base pairing. (B) DNA helix bundles (left),9–10 2-D arrays (middle),11–12 and 3-D objects (right).13–15 (C) DNA origami for constructing 2-D nanostructures18 and (D) 3-D architectures - hollow box (left),19 multi-layer monolith and a square-toothed gear(middle),5, 22 and semi-sphere and a nanoflask (right).23 Figures are reproduced with permissions from ACS, AAAS and NPG.