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. 2013 May 9;14(Suppl 8):S6. doi: 10.1186/1471-2105-14-S8-S6

Table 2.

Energy potentials (kcal/mole) computed from the propensities of amino acid residues at different positions in amyloid and non-amyloid hexa-peptides

Amyloid Position
1 2 3 4 5 6
Amyloid
Ala 0.510 0.814 1.469 1.056 0.000 0.814
Asp 0.848 0.848 1.259 0.000 0.000 0.606
Cys 0.000 -0.434 -0.021 -0.021 0.000 -0.263
Glu 0.639 0.335 0.135 0.468 1.294 -0.974
Phe -0.060 -0.231 -0.833 -0.060 -0.806 -0.300
Gly -0.007 0.596 1.422 0.000 0.000 1.009
His -0.386 0.027 0.000 0.681 0.000 0.000
Ile 0.408 -0.137 1.235 -1.225 -1.460 0.580
Lys 0.080 0.000 0.000 1.239 0.000 0.826
Leu 0.310 -0.103 0.231 -0.252 1.056 0.310
Met -0.291 0.255 0.668 0.000 0.000 -0.491
Asn -0.142 0.685 0.442 -0.688 0.000 0.029
Pro 0.000 0.000 0.000 0.000 0.000 0.000
Gln 0.340 -0.314 -0.165 0.000 0.996 -0.534
Arg 0.734 0.000 0.000 0.000 0.000 0.000
Ser -1.036 0.602 0.098 1.259 1.259 -0.171
Thr 0.829 -1.089 0.000 0.175 1.244 0.083
Val -0.014 -0.071 -1.191 1.355 0.000 -0.071
Trp -0.413 0.000 -0.546 -0.747 0.413 0.413
Tyr -0.204 -0.353 0.956 -0.283 -0.798 -0.112
Non-amyloid
Ala 0.423 -0.070 0.622 0.927 0.622 0.757
Asp 0.214 0.718 0.306 0.548 0.414 0.306
Cys 0.000 0.093 -0.320 0.500 0.000 0.000
Glu -0.073 -0.206 -0.244 -0.021 0.340 -0.874
Phe -0.250 0.054 -0.772 -0.492 -0.864 -0.359
Gly 0.710 0.375 0.879 0.467 1.528 0.225
His -0.165 0.139 0.382 0.139 0.382 0.382
Ile 0.280 0.108 0.280 -0.866 -1.122 0.038
Lys -0.370 0.285 0.192 0.393 0.285 0.393
Leu 0.516 -0.031 0.273 -0.423 0.423 0.011
Met 0.126 -0.178 0.369 0.778 0.778 -0.378
Asn -0.028 1.207 -0.270 -0.099 0.251 0.385
Pro 0.397 0.566 0.397 0.262 0.262 0.262
Gln 0.451 0.451 0.040 0.282 0.282 -0.052
Arg -0.050 0.604 0.604 0.300 0.848 0.192
Ser -0.827 0.132 0.132 0.303 0.716 0.061
Thr 0.117 -0.899 0.530 0.196 0.942 -0.125
Val 0.402 0.310 -0.681 0.645 0.310 0.645
Trp -0.130 0.114 -0.634 0.521 0.114 -0.130
Tyr -0.240 -0.360 0.413 -0.170 -0.503 0.243