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. 2013 May 15;8(5):e55918. doi: 10.1371/journal.pone.0055918

Table 4. Effect of screening case definitions on estimates of influenza-associated hospitalization annual incidence, Vadu, District Pune, India, May 2009–April 2011.

Screending definition # of patients meeting screening definition # (%) patients with specimens positive for influenza virus Adjusted influenza-associated hospitalization annual incidence per 10,000 persons % underestimate*
Acute medical hospitalization 3179 665 (20,9%) 44.1
ILI** 1632 454 (27.8%) 30.1 32%
ARI*** 2183 566 (25.9%) 37.5 15%
FARI 1659 455 (27.4%) 30.1 32%
SARI 87 20 (23.0%) 1.3 97%
*

% underestimate defined as ((1-estimated hospitalization incidence based on use of the given screening definition)/estimated hospitalization incidence based on use of all acute medical hospitalizations as a screening definition) expressed as a percentage).

**

Influenza-like illness (ILI) was defined as fever and either cough or sore throat.

***

Acute respiratory illness (ARI) was defined as >1 of the following: cough, nasal discharge, sore throat, or shortness of breath (based on history).

Febrile acute respiratory illness (FARI) was defined as the presence of ARI plus fever.

For persons >5 years, severe acute respiratory illness (SARI) was defined as the presence of ILI and either shortness of breath or difficulty breathing.

For children <5 years, SARI was defined as pneumonia or severe pneumonia as defined by the Integrated Management of Childhood Illness guidelines as any of the following: any general danger sign (i.e. unable to drink or breastfeed, vomiting, convulsions, lethargic, or unconscious), chest indrawing, stridor, or fast breathing on examination.