Table 4. Effect of screening case definitions on estimates of influenza-associated hospitalization annual incidence, Vadu, District Pune, India, May 2009–April 2011.
Screending definition | # of patients meeting screening definition | # (%) patients with specimens positive for influenza virus | Adjusted influenza-associated hospitalization annual incidence per 10,000 persons | % underestimate* |
Acute medical hospitalization | 3179 | 665 (20,9%) | 44.1 | — |
ILI** | 1632 | 454 (27.8%) | 30.1 | 32% |
ARI*** | 2183 | 566 (25.9%) | 37.5 | 15% |
FARI† | 1659 | 455 (27.4%) | 30.1 | 32% |
SARI‡ | 87 | 20 (23.0%) | 1.3 | 97% |
% underestimate defined as ((1-estimated hospitalization incidence based on use of the given screening definition)/estimated hospitalization incidence based on use of all acute medical hospitalizations as a screening definition) expressed as a percentage).
Influenza-like illness (ILI) was defined as fever and either cough or sore throat.
Acute respiratory illness (ARI) was defined as >1 of the following: cough, nasal discharge, sore throat, or shortness of breath (based on history).
Febrile acute respiratory illness (FARI) was defined as the presence of ARI plus fever.
For persons >5 years, severe acute respiratory illness (SARI) was defined as the presence of ILI and either shortness of breath or difficulty breathing.
For children <5 years, SARI was defined as pneumonia or severe pneumonia as defined by the Integrated Management of Childhood Illness guidelines as any of the following: any general danger sign (i.e. unable to drink or breastfeed, vomiting, convulsions, lethargic, or unconscious), chest indrawing, stridor, or fast breathing on examination.