Table 2.
Characteristics of the eight patients with sarcoidosis and glomerular disease occurring simultaneously
| pt1 | pt2 | pt3 | pt4 | pt5 | pt6 | pt7 | pt8 | pt9 | |
|---|---|---|---|---|---|---|---|---|---|
| Type of GD |
MN |
MN |
FSGS |
FSGS |
IgAN |
IgAN |
IgAN |
MCNS |
MN |
| Age at GD diagnosis (years) |
51.9 |
50.6 |
56.4 |
46.3 |
52.5 |
22.2 |
25.2 |
28.7 |
44 |
| Proteinuria level (g/d) |
1.8 |
4.3 |
1.7 |
6.6 |
1 |
1.3 |
1 |
3 |
7 |
| GFR (ml/min/1.73 m2) |
35 |
69 |
56 |
60 |
97 |
96 |
81 |
92 |
89 |
| Serum Albumin (g/L) |
43 |
31.6 |
38 |
27 |
17 |
35 |
38 |
29 |
16 |
| GTIN (+ present -absent) |
+ |
- |
+ |
- |
+ |
+ |
- |
+ |
+ |
| Affected organs |
Lymph nodes Erythema Nodosum |
Spleen Lymph nodes parotitis |
Lung Skin |
Lung Lymp nodes |
Lung Lymph nodes Liver Spleen Bone marrow Salivary glands |
Lung Lymph nodes Liver Spleen parotidis |
Lymph nodes |
Lymph nodes Skin epididymitis |
Lymph nodes Salivary glands |
| Radiographic classification (stage) |
1 |
0 |
2 |
2 |
3 |
1 |
1 |
1 |
1 |
| Steroid treatment |
yes |
no |
yes |
yes |
yes |
yes |
yes |
yes |
yes |
| Remission of GD with steroids |
CR |
no |
CR |
no |
PR |
CR |
CR |
PR |
PR |
| Remission of sarcoidosis with steroids |
no |
no |
no |
no |
yes |
no |
yes |
yes |
yes |
| Other immunosuppressive treatment (date of introduction) |
Plaquenil (M7) |
|
Plaquenil (M19) |
Aza (M13) |
|
Aza (M18) |
|
MMF (M12) |
|
| Duration of follow-up (years) |
9 |
0.6 |
2.7 |
5 |
0.6 |
3.3 |
10.8 |
2 |
0.6 |
| GFR at the end of follow-up (mL/min/1.73 m2) | 56.8 | 67 | died | dialysis | 86.6 | 120.4 | 78.1 | 80 | 72 |
GD: Glomerular disease, MN: membranous nephropathy, IgAN: IgA nephropathy, MCNS: minimal change nephrotic syndrome, FSGS: focal and segmental glomerulosclerosis, GTIN: granulomatous tubulointerstitial nephritis, GFR: glomerular filtration rate, Aza: azathioprine, MMF: Mycophenolate Mofetil, CR: complete remission, PR: partial remission.