Table 1. Patient characteristics.
| All | Tuberculosis$ | QFT-IT positive non-cases | M.tb uninfected | P value 1 | P value 2 | |
| N (%) | 76 | 19 (25) | 26 (34.2) | 31(40.8) | – | – |
| Age, Months (IQR) | 37.6 (13.8–48.7) | 36.7 (6.0–55.0) | 41.4 (18.1–55.6) | 35.1 (14.1–38.3) | 0.552 | 0.223 |
| Males, n(%) | 42 (55.3) | 13 (68.4) | 10 (38.5) | 19 (61.3) | 0.28 | 0.052 |
| HIV infected, n(%) | 22(29.0) | 4(21.0) | 9(34.6) | 9(29.0) | 0.480 | 0.560 |
| Quantiferon results≠ | ||||||
| Positive, n (%) | 41(54.0) | 15 (79.0) | 26 (100.0) | 0 (0.0) | 0.027 | 0.027 |
| Negative, n (%) | 33 (43.0) | 2 (10.5) | 0 (0.0) | 31 (100.0) | <0.0001 | – |
| Indeterminate, n(%) | 2 (2.6) | 2 (10.5) | 0 (0.0) | 0 (0.0) | – | – |
Two of the children had contained pulmonary TB disease (Ghon focus), 12 had uncontained pulmonary TB and 5 had disseminated TB disease. Of the 12 children with uncontained pulmonary TB, 8 had alveolar opacification with pleural effusion (n = 2) or without effusion (n = 6), 2 had expansile pneumonia (n = 1 with obstruction and collapse), and 2 had bronchopneumonic spread (n = 1 with pleural effusion). Of the 5 children with disseminated disease, 2 had miliary TB, 2 had TB meningitis and miliary TB, and 1 had spinal TB with alveolar opacification.
Positive: Nil IFN-γ ≤8.0 IU/ml and TB Ag-Nil ≥0.35 IU/ml and ≥25% of Nil value; Negative: Nil IFN-γ ≤8.0 IU/ml and TB Ag-Nil <0.35 IU/ml and Mitogen-Nil ≥0.5 IU/ml, or Nil IFN-γ ≤8.0 IU/ml and TB Ag-Nil ≥0.35 IU/ml and <25% of Nil value and Mitogen-Nil ≥0.5 IU/ml; Indeterminate: Nil IFN-γ >8.0 IU/ml, or Nil IFN-γ <8.0 IU/ml and TB Ag-Nil <0.35 IU/ml and Mitogen-Nil <0.5 IU/mL, or Nil IFN-γ <8.0 IU/ml and TB Ag-N ≥0.35 IU/ml and <25% of Nil value and Mitogen <0.5 IU/ml.
P-value 1: Number of individuals with variable/outcome and with TB vs number with variable but without TB, P-value 2: Number of individuals with variable and with LTBI vs number with variable and with Active TB.
IQR: Interquartile range.