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. Author manuscript; available in PMC: 2013 Jun 19.
Published in final edited form as: Neurocase. 2012 Apr 18;19(3):295–301. doi: 10.1080/13554794.2012.667124

Figure 1.

Figure 1

Structural MRI comparison. MR images of Patient 1 (A, B), an apoE ε4 homozygote, taken 1 year after initial presentation, showed gray matter atrophy in FTLD-vulnerable regions, including the lateral and medial prefrontal cortex, anterior cingulate cortex, and frontoinsulae (A, arrow), as well as thinning of the anterior corpus callosum (B, arrowhead) and ex vacuo ventricular enlargement. MR images of Patient 2 (C, D), an apoE ε3 homozygote, taken 2 years after initial presentation, showed less significant atrophy in these regions. R = right, L = left.