Table 1.
Comparison of metabolite concentrations measured in non-ischemic brain in vivo by MRS in different studies*.
| Lac | GABA | tCr | Glu | NAA | Tau | Gln | Ins | PCho | ||
|---|---|---|---|---|---|---|---|---|---|---|
| Striatum (33,35,36) |
1.3–1.8 | 1.1–2.3 | 5.8–8.5 | 7.9–8.6 | 7.1–7.7 | 1.9–10.9 | 1.7–3.7 | 3.7–6.3 | 1.0–1.9 | |
| Cortex (34–36) |
1–1.5 | 0.8–2.2 | 5.4–8.5 | 8.5–11 | 6.9–10 | 3.3–8.0 | 2.3–3.4 | 3–6.1 | 0.6–1.0 | |
| This study |
Contra | 0.8±1.0 | 3.8±1.0 | 8.4±0.9 | 13.8 ±1.8 | 10.3±1.0 | 11.9±2.8 | 4.6±0.9 | 5.4±1.2 | 1.8±0.4 |
| Lesion | 22.2±6.0 | 6.7±1.6 | 7.9±1.1 | 8.3±1.2 | 8.9±0.7 | 7.5±2.0 | 2.5±1.5 | 6.1±1.3 | 1.4±0.5 | |
*
The voxels in our study cover both striatum and lower parietal cortex. The values in Ref. (35) are for rats of 4 weeks old. All concentrations are in units of µmol/g. The errors are standard deviations across animals. The data on the lesion side were measured during the first period of 30 – 110 min after MCAO.