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. 2013 May 15;8(5):e63488. doi: 10.1371/journal.pone.0063488

Figure 5. Ang II-mediated blockage of K+ currents lies downstream of AT2R/ERK pathway.

Figure 5

A) Representative K+ current traces showing response of Ang II, Ang II+ PD123319, Ang II+Losartan, CGP42112A or Ang II+U0126 in NSCs evoked from −80 to 80 mV. NSCs were pre-treated with vehicle, Losartan, PD123319, or U0126 for 1 hour followed by incubation with Ang II or CGP42112A for 24 hours. B) Mean data of peak K+ current change from −80 to 80 mV. C) Peak K+ current change at +80 mV. *P<0.05 vs untreated control group, #P<0.05 vs Ang II- treated group; n = 10 in each group.