Table 1.
Age (weeks) | 2 | 4 | 7 | 11 | 18 | 30 | |
---|---|---|---|---|---|---|---|
Number | OLETF | 22 | 10 | 10 | 10 | 8 | 6 |
LETO | 10 | 10 | 10 | 9 | 10 | 12 | |
BW (g) | OLETF | 32 ± 1 * | 95 ± 2 * | 240 ± 4 * | 352 ± 5 * | 533 ± 11 * | 573 ± 8 * |
LETO | 26 ± 1 | 89 ± 2 | 189 ± 5 | 305 ± 4 | 441 ± 12 | 473 ± 10 | |
LKW (g) | OLETF | 0.19 ± 0.01 * | 0.54 ± 0.02 * | 1.11 ± 0.03 * | 1.13 ± 0.05 | 1.62 ± 0.04 * | 1.54 ± 0.05 * |
LETO | 0.15 ± 0.01 | 0.42 ± 0.01 | 0.79 ± 0.02 | 0.92 ± 0.03 | 1.13 ± 0.03 | 1.25 ± 0.01 | |
LKW/BW (* 1000) | OLETF | 5.8 ± 0.1 | 5.8 ± 0.2 * | 4.7 ± 0.2 * | 3.2 ± 0.2 | 3.0 ± 0.1 * | 2.7 ± 0.1 * |
LETO | 6.0 ± 0.1 | 4.6 ± 0.1 | 4.2 ± 0.2 | 3.0 ± 0.1 | 2.6 ± 0.1 | 2.3 ± 0.1 | |
PPBG (mmol/l) | OLETF | 8.1 ± 0.3 | 8.1 ± 0.3 | 8.0 ± 0.1 | 10.7 ± 0.7* | 10.7 ± 0.9* | |
LETO | 7.2 ± 0.2 | 7.6 ± 0.2 | 7.9 ± 0.3 | 8.4 ± 0.4 | 8.4 ± 0.2 |
Values are means ± standard error
p < 0.05 vs. LETO rats at the same age. BW: body weight; LKW: left kidney weight; PPBG: postprandial blood glucose