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Collagen IV tracks connect vascular islands to nearby networks and other vascular islands. (A–C) An example of PECAM-positive endothelial cells along vascular islands (arrows) with positive collagen IV connections to nearby networks (arrowheads). (D–F) Higher magnification images of PECAM and collagen IV labeling within the area defined by the rectangle. Blind ended capillary segments still connected to a network are indicated by “c.” Lymphatic vessels are indicated by “L.”
