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. 1988 Oct;8(10):4547–4551. doi: 10.1128/mcb.8.10.4547

Differential expression of type-specific c-abl mRNAs in mouse tissues and cell lines.

M W Renshaw 1, M A Capozza 1, J Y Wang 1
PMCID: PMC365533  PMID: 2460747

Abstract

The mammalian c-abl proto-oncogene produces mRNAs with 5' heterogeneity from two distinct promoters and the alternative splicing of variable 5' exons. By using quantitative RNase protection assays, the relative abundance of two major c-abl mRNAs, type I and type IV, in several mouse tissues and cell lines has been determined. Our results demonstrate that the level of type IV c-abl mRNA is rather constant, whereas that of the type I mRNA varies over a 10-fold range in different tissues and cell types. This finding has interesting implications for the function of the two c-abl proteins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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