Table 1.
For all regions showing significant differences between the two groups (Met/Met > Val/Met), Brodman Area (BA), volume in mm3, MNI coordinates at peak, p-value for peak activation and directionality of the observed effect.
| region | BA | vol | X | Y | Z | p-value | direction |
|---|---|---|---|---|---|---|---|
| precuneus | 7 | 12616 | 28 | −54 | 16 | <0.0001 | 1>2 |
| Superior Temporal Gyrus | 21/22 | 6400 | 56 | −28 | −1 | <0.0001 | 1>2 |
| Parahippocampa Gyrus | 19 | 5080 | 28 | −51 | −2 | 0.0002 | 1>2 |
| Middle Occipital Gyrus | 18 | 1496 | −18 | −86 | −15 | 0.001 | 1>2 |
| Parahippocampa Gyrus | 30 | 1048 | −22 | −42 | −6 | 0.0017 | 1>2 |
| Lingual Gyrus | 18 | 952 | −10 | −64 | 2 | 0.0023 | 1>2 |
| Precentral Gyrus | 6 | 944 | −34 | −14 | 44 | 0.0006 | 1>2 |
| Superior Temporal Gyrus | 42 | 664 | 70 | −24 | 10 | 0.0005 | 1>2 |
| Superior Parietal Lobule | 7 | 584 | −44 | −62 | 54 | 0.0002 | 1>2 |
| Insula | 13 | 584 | −42 | −36 | 24 | 0.0028 | 1>2 |
| Superior Frontal Gyrus | 10 | 504 | −10 | 68 | −6 | 0.0007 | 1>2 |
| Culmen | 480 | 24 | −60 | −30 | 0.0011 | 1>2 | |
| Precuneus | 7 | 408 | −20 | −82 | 50 | 0.0018 | 1>2 |
| Middle Frontal Gyrus | 46 | 376 | 52 | 29 | 30 | 0.0008 | 1>2 |
| Postcentral Gyrus | 43 | 368 | 70 | −14 | 20 | 0.0029 | 1>2 |
| Lingual Gyrus | 18 | 328 | 6 | −86 | −6 | 0.0034 | 1>2 |
| Culmen | 296 | 12 | −42 | −24 | 0.0035 | 1>2 | |
| Middle Temporal Gyrus | 20 | 272 | −64 | −46 | −16 | 0.0012 | 1>2 |
| Inferior Frontal Gyrus | 47 | 216 | −42 | 22 | −14 | 0.005 | 1>2 |
| Middle Temporal Gyrus | 21 | 144 | −64 | −30 | 0 | 0.0049 | 1>2 |
| Precentral Gyrus | 6 | 120 | 20 | −16 | 54 | 0.0042 | 1>2 |
| Superior Frontal Gyrus | 10 | 112 | 30 | 62 | −4 | 0.0067 | 1>2 |
| Culmen | 36 | 104 | −12 | −46 | −24 | 0.0064 | 1>2 |
| Angular Gyrus | 39 | 88 | −54 | −62 | 36 | 0.0051 | 1>2 |
| Lentiform Nucleus | 80 | 30 | −16 | −6 | 0.0037 | 1>2 | |
| Inferior Frontal Gyrus | 11 | 1416 | 12 | 36 | −22 | −0.0002 | 2>1 |
| Middle Frontal Gyrus | 11 | 520 | −20 | 44 | −12 | −0.0005 | 2>1 |
| Cuneus | 19 | 296 | 12 | −96 | 24 | −0.0003 | 2>1 |
| Inferior Frontal Gyrus | 10 | 168 | 48 | 48 | 0 | −0.0013 | 2>1 |
| Cuneus | 17 | 88 | 10 | −98 | 0 | −0.0068 | 2>1 |
Met/Met= 1, Val/Val= 2