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Human cells do not respond to CMA. (A–E) Primary human PBMCs and fibroblasts were transfected with poly(I:C), pppRNA, ISD and c-diGMP, or stimulated with LPS and decreasing concentrations of CMA (4000—125 μg/ml in twofold dilutions). IP-10, IL-6 and IFNα levels in the supernatants of stimulated PBMCs (A–C) and fibroblasts (D,E) were determined by enzyme-linked immunosorbent assay. Representative results out of three independent experiments are depicted.
