Figure 4.

Effect of RV extract on the mast cell infiltration in DNFB-induced allergic contact dermatitis mice. (a) Toluidine blue-stained ear sections. White arrowhead and black arrowhead indicate granulated mast cells and degranulated mast cells, respectively. Scale bar = 50 μm (top panel); scale bar = 20 μm (bottom panel). (b) Quantitative analysis of the number of mast cells. Numbers of mast cells are presented as means ± standard error (S.E.) of three independent experiments (n = 5 per group) (^a P < 0.001 versus control; ^b P < 0.01 versus DNFB).