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Effects of XXMD on MMP-9, MMP-2, and VEGF expressions 24 h after reperfusion. (a) Representative protein bands from western blotting for MMP-9, -2, and VEGF in the penumbra of the ischemic cortex. (b) Integrated density for MMP-9,-2, and VEGF. The expression levels of MMP-9, MMP-2, and VEGF under XXMD treatment were significantly reduced compared to the IR group. Data are reported as the mean ± SEM, n = 3 for each group. *P < 0.05 versus the IR group.
