Figure 4.

The increase in AUC0–∞ (a) and the decrease in CL (b) of MDZ (10 mg/kg, i.v.) after treatment with baicalin at a single dose of 0.225 g/kg (n = 8) or 0.45 g/kg (n = 9) or at a dose of 0.90 g/kg once for 1 day and the same dose for 7 days (n = 8).