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. Author manuscript; available in PMC: 2014 Apr 29.
Published in final edited form as: Neurosci Lett. 2013 Feb 26;541:116–119. doi: 10.1016/j.neulet.2013.02.026

Figure 3. VA neuroprotection of α-Syn-overexpression in DA neurons is dependent on the ERK-MAPK signaling pathway.

Figure 3

(A) Cell-specific RNAi depletion of mek-2 negates the dopaminergic neuroprotection provided by VA at all concentrations of examined compared to empty vector (EV) control, where neuroprotection is still observed at 1, 2, and 3 mM VA. (B) Similar to A, mpk-1 depletion reverses neuroprotection of VA in dopaminergic neurons at 3 mM VA compared to EV control. P < 0.05; Student’s t-test.