Figure 3. Quantization of MECIII persistent Up state durations in units of neocortical UDS.
a) Matrix composed of all 237 membrane potential Up states from an example MECIII neuron, aligned to the MECIII Up transition, and ordered from top to bottom by increasing MECIII Up state duration. The vertical black line shows the onset of the MECIII Up state, and the red trace shows the time of termination of each MECIII Up state. b) Matrix of corresponding neocortical LFP traces during each of the MECIII Up states shown in a. Black and red lines are the same as in a. c) I–IV Example traces from the MECIII membrane potential and neocortical LFP, taken from the locations of the matrices indicated by the black arrows. Action potentials are indicated by tick marks, and 1 z is subtracted from the LFP signal for visual comparison with the membrane potential. d) Histogram of MECIII Up state durations in units of neocortical UDS cycles. e) The distribution of Up state durations averaged across all cells, in units of neocortical UDS cycles, is quantized with nearly integer spacing.
