Table 1.
Summary comparison of properties of MECIII and LECIII UDS.
| MECIII (n=41) | LECIII (n=13) | p-value† | |
|---|---|---|---|
| Up state MP(mV) | −52.5 ± 0.62 | −68 ± 2.0 | 3.2×10−7 |
| Down state membrane potential (mV) | −74.9 ± 0.83 | −78 ± 1.4 | 0.12 |
| Avg. Up state firing rate (Hz) | 5.9 ± 0.30 | 1.2 ± 0.39 | 2.8×10−7 |
| Overall avg. firing rate (Hz) | 3.4 ± 0.19 | 0.4 ± 0.14 | 9.2×10−8 |
| Avg. Up state duration (s) | 1.80 ± 0.080 | 1.00 ± 0.056 | 2.0×10−7 |
| Avg. Down state duration (s) | 1.34 ± 0.089 | 1.9 ± 0.45 | 0.018 |
| Avg. lag from neocortical Up transition (ms) | 220 ± 16 | 120 ± 18 | 2.4×10−3 |
| Avg. lag from neocortical Down transition (ms) | 540 ± 36 | 30 ± 26 | 1.2×10−7 |
| Percent of persistent Up states | 15 ± 1.4 | 1.1 ± 0.29 | 7.4×10−8 |
Numbers are reported as mean ± SEM
Wilcoxon rank sum test (two-sided) for equal medians of MECIII and LECIII groups.