Skip to main content
. Author manuscript; available in PMC: 2013 May 16.
Published in final edited form as: Acta Pharm Sin B. 2012 Apr 1;2(2):213–219. doi: 10.1016/j.apsb.2012.02.008

Table 3.

Predicted log P and log D values and water solubilities of 3 and 10*.

Parameter Compound
3 10
Water solubility (mg/L, pH 7.4) 8.4 18
log P 4.44 3.84
log D (pH 7.4) 4.43 3.38
*

The octanol-water partition coefficient log P and apparent distribution coefficient log D values were calculated by using ACD programs.