FIGURE 1:
arl-8(tm2504) mutants are defective in the removal of germ cell corpses. (A) Nomarski images of gonad arms in wild-type or arl-8(tm2504) adult hermaphrodites 48 h after the L4 larval stage. Germ cell corpses are marked with arrowheads. Bars, 10 μm. (B) Germ cell corpses of one gonad arm from each animal were scored every 12 h after the L4 larval stage. Fifteen animals were scored for each strain, and data are expressed as mean ± SEM. (C) The increased germ cell corpse phenotype of arl-8(tm2504) animals was rescued by Pced-1::arl-8::venus. Germ cell corpses of one gonad arm from the indicated animals were scored after the L4 larval stage. More than 10 animals were scored for each strain, and the data are expressed as mean ± SEM. **p < 0.01 by Student's t test. (D) Histogram summarizing cell corpse duration the germline of the indicated animals. More than 15 cell corpses were monitored in each strain.