Table 2.
Single-SNP analysis
|
Model |
Genotype |
Status = Case |
Status = Control |
OR (95% CI) |
p-value |
AIC |
BIC |
|---|---|---|---|---|---|---|---|
| (N, %) | (N, %) | ||||||
| Co-dominant |
C/C |
41 (56.9%) |
134 (44.4%) |
1.00 |
0.051 |
353.0 |
372.6 |
| |
T/C |
21 (29.2%) |
133 (44.0%) |
2.00 (1.11-3.62) |
|
|
|
| |
T/T |
10 (13.9%) |
35 (11.6%) |
1.01 (0.45-2.27) |
|
|
|
| Dominant |
C/C |
41 (56.9%) |
134 (44.4%) |
1.00 |
0.056 |
353.3 |
369.0 |
| |
T/C-T/T |
31 (43.1%) |
168 (55.6%) |
1.68 (0.99-2.86) |
|
|
|
| Recessive |
C/C-T/C |
62 (86.1%) |
267 (88.4%) |
1.00 |
0.480 |
356.5 |
372.2 |
| |
T/T |
10 (13.9%) |
35 (11.6%) |
0.75 (0.35-1.64) |
|
|
|
| Over-dominant |
C/C-T/T |
51 (70.8%) |
169 (56.0%) |
1.00 |
0.015* |
351.0 |
366.7 |
| |
T/C |
21 (29.2%) |
133 (44.0%) |
2.00 (1.13-3.54) |
|
|
|
| Log-additive | 1.24 (0.83-1.86) | 0.280 | 355.8 | 371.5 |
SNP: rs20541 Percentage of typed samples: 374/374 (100%).
rs20541 association with response status (n = 374, adjusted by sex + age).
* p < 0.05 indicates statistical significance.