Table 4.
Single-SNP analysis
|
Model |
Genotype |
Status = Case |
Status = Control |
OR (95% CI) |
p-value |
AIC |
BIC |
|---|---|---|---|---|---|---|---|
| (N, %) | (N ,%) | ||||||
| Co-dominant |
A/A |
56 (77.8%) |
187 (62.8%) |
1.00 |
0.028 |
350.1 |
369.6 |
| |
A/G |
14 (19.4%) |
105 (35.2%) |
2.26 (1.19-4.32) |
|
|
|
| |
G/G |
2 (2.8%) |
6 (2.0%) |
0.72 (0.13-4.02) |
|
|
|
| Dominant |
A/A |
56 (77.8%) |
187 (62.8%) |
1.00 |
0.016 |
349.4 |
365.1 |
| |
A/G-G/G |
16 (22.2%) |
111 (37.2%) |
2.07 (1.12-3.83) |
|
|
|
| Recessive |
A/A-A/G |
70 (97.2%) |
292 (98.0%) |
1.00 |
0.550 |
354.9 |
370.5 |
| |
G/G |
2 (2.8%) |
6 (2.0%) |
0.58 (0.10-3.23) |
|
|
|
| Over-dominant |
A/A-G/G |
58 (80.6%) |
193 (64.8%) |
1.00 |
0.0081* |
348.2 |
363.9 |
| |
A/G |
14 (19.4%) |
105 (35.2%) |
2.29 (1.20-4.35) |
|
|
|
| Log-additive | 1.76 (1.00-3.10) | 0.042 | 351.1 | 366.7 |
SNP: rs1801275 Percentage of typed samples: 370/374 (98.93%).
rs1801275 association with response status (n = 370, adjusted by sex + age).
Note: AIC: Akaike Information Criterion; BIC: Bayesian Information Criterion.
* p < 0.05 indicates statistical significance.