Table 2.
Top ten chromatin motifs and TF annotation
| Region | Motif | Antisense motif | P value |
Annotation |
Ref | ||
|---|---|---|---|---|---|---|---|
| TFe | hDPI logo | hDPI motif | |||||
|
Genome-wide regions |
CACGTG |
CACGTG |
7.61E-08 |
|
USF1 USF2 |
MAX USF1 USF2 CREB1 TSNAX ZBTB7A TFEB IRF3 MLX |
[21,22,29] |
| |
CTCCTGAC |
GTCAGGAG |
2.36E-06 |
RXR/RAR |
|
|
[24,25] |
| |
CTGCAG |
CTGCAG |
3.34E-06 |
|
|
MAX IRF3 ZBTB25 |
[21] |
| |
TTTAGTAGAG |
CTCTACTAAA |
3.42E-06 |
|
|
|
|
| |
AGTAGAGA |
TCTCTACT |
5.71E-06 |
|
|
|
|
| |
GTGAAACCC |
GGGTTTCAC |
7.98E-06 |
|
HCFC2 ZNF193 RAB18 |
|
[28] |
| |
GGTGAAACCC |
GGGTTTCACC |
1.23E-05 |
|
HCFC2 ZNF193 RAB18 |
|
[28] |
| |
CTCCTGACCT |
AGGTCAGGAG |
1.33E-05 |
RXR/RAR |
RXRA CREB1 ZNF313 ZNF655 |
MAX USF2 RCOR3 RBM9 GLRX2 ZNF606 CBFA2T3 YBX1 HTATIP IRF3 ESRRA |
[24,25] |
| |
AGGTCAGGA |
TCCTGACCT |
1.41E-05 |
RXR/RAR |
RXRA CREB1 ZNF313 ZNF655 |
MAX USF2 RCOR3 RBM9 GLRX2 ZNF606 CBFA2T3 YBX1 HTATIP IRF3 ESRRA |
[24,25] |
| |
TCAGGA |
TCCTGA |
1.85E-05 |
|
|
|
|
|
Intergenic regions |
CACGTG |
CACGTG |
1.53E-07 |
|
USF1 USF2 |
MAX USF1 USF2 CREB1 TSNAX ZBTB7A TFEB IRF3 MLX |
[21,22,29] |
| |
TGTATACA |
TGTATACA |
1.59E-05 |
|
|
|
|
| |
ATCACAA |
TTGTGAT |
2.45E-05 |
SOX9 |
|
|
[25] |
| |
ATGTATACA |
TGTATACAT |
3.20E-05 |
|
|
|
|
| |
GGGTTTCAC |
GTGAAACCC |
3.63E-05 |
|
HCFC2 ZNF193 RAB18 |
|
[28] |
| |
GGTGAAACCC |
GGGTTTCACC |
5.67E-05 |
|
HCFC2 ZNF193 RAB18 |
|
[28] |
| |
ATGTATACAT |
ATGTATACAT |
5.87E-05 |
|
|
|
|
| |
GGTGAAAC |
GTTTCACC |
8.17E-05 |
|
ZNF193 RAB18 |
|
|
| |
CCCGGG |
CCCGGG |
1.24E-04 |
|
|
|
|
| |
GGTGAAACC |
GGTTTCACC |
1.37E-04 |
|
ZNF193 RAB18 |
|
|
|
Genic regions |
CAGGCTGGA |
TCCAGCCTG |
1.58E-06 |
|
|
|
|
| |
ACTCCAGCCT |
AGGCTGGAGT |
2.46E-06 |
|
|
|
|
| |
CTCCAGCCTG |
CAGGCTGGAG |
2.66E-06 |
|
|
|
|
| |
TCCAGCCTGG |
CCAGGCTGGA |
6.96E-06 |
|
PIR |
MAX SIRT2 ZNF34 RFXANK ZBTB7A SCAND2 TSNAX KHDRBS1 ZNF655 TP73 IRF3 NFATC1 |
[21] |
| |
AGGCTGGA |
TCCAGCCT |
6.96E-06 |
|
|
|
|
| |
GGAGGA |
TCCTCC |
1.16E-05 |
|
|
|
|
| |
CTCCAGCCT |
AGGCTGGAG |
1.17E-05 |
|
|
|
|
| |
TCAGAT |
ATCTGA |
1.57E-05 |
|
|
|
|
| |
GGAGTG |
CACTCC |
1.57E-05 |
|
|
|
|
| CACTCCA | TGGAGTG | 2.17E-05 | MEF2A | [27] | |||