Table 2.

Voriconazole dosing characteristics, drug level monitoring, and duration of therapy

Voriconazole therapy	Median value[(IQR]
Voriconazole serial drug levels (mg/L)
Initial drug level (n = 108)	2.35 [0.7, 3.8]
Second drug level (n = 51)	2.00 [0.5, 3.5]
Third drug level (n = 26)	1.35 [0.6, 7.7]
Voriconazole loading dose (mg/dose; n = 59)	400 [350, 480]
Voriconazole maintenance dose (mg/dose; n = 107)	260 [200,300]
Patient weight (kg; n = 107)	71.3 [60.5, 85.8]
Duration of voriconazole therapy in days (n = 85)	35 [13, 92]
Days between initiation of voriconazole to first drug level (n = 100)	11 [3,164]
Hours between last dose and trough drug level (n = 64)	11.3 [8.9-12.0]