Table 3.
30-day-mortality according to LRTI manifestation group overall and stratified by subgroups
|
Prognostic factor |
No infiltrate and no bacteraemia patients |
Infiltrate without bacteraemia patients |
Bacteraemia patients |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n (%) | Crude MRR (95 % CI) a | Adjusted MRR (95% CI) a,b | n (%) | Crude MRR (95% CI) a | Adjusted MRR (95% CI) a,b | n (%) | Crude MRR (95 % CI) a | Adjusted MRR (95% CI) a,b | ||
| All patients |
9 (5) |
1.0 (ref.) |
1.0 (ref.) |
27 (11) |
2.4 (1.1-5.0) |
1.9 (0.9-4.1) |
54 (21) |
4.8 (2.4-9.6) |
4.1 (2.0-8.5) |
|
| Age group (years) | ||||||||||
| |
15-49 |
0 (0) |
1.0 (ref.) |
1.0 (ref.) |
3 (8) |
NA |
NA |
2 (4) |
NA |
NA |
| |
50-74 |
5 (4) |
1.0 (ref.) |
1.0 (ref.) |
13 (10) |
2.3 (0.8-6.6) |
2.1 (0.7-6.0) |
28 (22) |
5.5 (2.1-14.3) |
5.2 (2.0-13.8) |
| |
≥75 |
4 (7) |
1.0 (ref.) |
1.0 (ref.) |
11 (13) |
1.8 (0.6-5.8) |
1.6 (0.5-5.3) |
24 (28) |
4.1 (1.4-11.9) |
3.3 (1.1-9.9) |
| Sex |
|
|
|
|
|
|
|
|
|
|
| |
Women |
3 (4) |
1.0 (ref.) |
1.0 (ref.) |
7 (8) |
2.2 (0.6-8.3) |
2.2 (0.6-9.0) |
20 (16) |
4.7 (1.4-15.9) |
4.3 (1.2-15.6) |
| |
Men |
6 (5) |
1.0 (ref.) |
1.0 (ref.) |
20 (13) |
2.3 (0.9-5.8) |
1.8 (0.7-4.5) |
34 (24) |
4.9 (2.1-11.7) |
4.2 (1.7-10.3) |
| Comorbidity index | ||||||||||
| |
Index low (0) |
1 (3) |
1.0 (ref.) |
1.0 (ref.) |
4 (6) |
2.1 (0.2-18.6) |
1.5 (0.2-14.7) |
15 (15) |
5.7 (0.7-42.8) |
4.1 (0.5-32.5) |
| |
Index medium (1–2) |
2 (2) |
1.0 (ref.) |
1.0 (ref.) |
13 (14) |
7.1 (1.6-31.5) |
5.8 (1.3-26.2) |
14 (17) |
8.9 (2.0-39.1) |
8.1 (1.8-36.8) |
| |
Index high (≥3) |
5 (9) |
1.0 (ref.) |
1.0 (ref.) |
10 (12) |
1.1 (0.4-3.1) |
0.8 (0.3-2.3) |
25 (31) |
3.5 (1.4-8.5) |
2.9 (1.2-7.3) |
| Chronic pulmonary disease c | ||||||||||
| |
Yes |
6 (5) |
1.0 (ref.) |
1.0 (ref.) |
12 (11) |
2.0 (0.7-5.3) |
1.3 (0.5-3.5) |
14 (24) |
4.8 (1.9-12.6) |
3.8 (1.4-10.3) |
| |
No |
3 (4) |
1.0 (ref.) |
1.0 (ref.) |
15 (11) |
3.1 (0.9-10.5) |
2.6 (0.7-9.4) |
40 (20) |
5.7 (1.8-18.6) |
4.5 (1.4-14.9) |
| CRP (mg/L) | ||||||||||
| |
<100 |
1 (1) |
1.0 (ref.) |
1.0 (ref.) |
8 (10) |
10.7 (1.3-85.8) |
11.3 (1.4-95.4) |
7 (32) |
35.6 (4.4-290) |
27.6 (2.8-267) |
| |
100-199 |
3 (6) |
1.0 (ref.) |
1.0 (ref.) |
6 (9) |
1.5 (0.4-6.1) |
1.1 (0.2-5.3) |
4 (13) |
2.2 (0.5-9.6) |
2.8 (0.5-15.7) |
| |
≥200 |
4 (17) |
1.0 (ref.) |
1.0 (ref.) |
12 (13) |
0.8 (0.3-2.4) |
0.6 (0.2-2.1) |
41 (21) |
1.3 (0.5-3.6) |
1.3 (0.5-3.6) |
| Leukocyte count (109/L) | ||||||||||
| |
<3,5 |
1 (100) |
1.0 (ref.) |
1.0 (ref.) |
3 (38) |
0.1 (0.0-2.1) |
NA |
8 (47) |
0.3 (0.0-2.3) |
0.2 (0.0-3.4) |
| |
3.5-8.7 |
0 (0) |
1.0 (ref.) |
1.0 (ref.) |
1 (4) |
NA |
NA |
7 (32) |
NA |
NA |
| |
8.8-14.9 |
3 (3) |
1.0 (ref.) |
1.0 (ref.) |
12 (12) |
3.7 (1.1-13.3) |
2.8 (0.7-10.4) |
8 (14) |
4.4 (1.2-16.4) |
2.7 (0.7-11.6) |
| ≥15.0 | 4 (6) | 1.0 (ref.) | 1.0 (ref.) | 10 (10) | 1.7 (0.5-5.4) | 1.3 (0.4-4.4) | 29 (19) | 3.5 (1.2-10.0) | 3.2 (1.1-9.5) | |
LRTI, lower respiratory tract infection; MRR, mortality rate ratio; CI, confidence interval; ref, reference; NA, not applicable because of too few events to calculate MRRs; CRP, C-reactive protein.
a MRR estimates are calculated using cox-regression.
b MRR estimates are adjusted for age, sex, comorbidity, smoking, and alcohol intake (except when stratified by variable).
c Chronic pulmonary disease: ICD-8: 490–493, 515–518. ICD-10: DJ40-DJ47, DJ60-DJ67, DJ68.4, DJ70.1, DJ70.3, DJ84.1, DJ92.0, DJ96.1, DJ98.2, DJ98.3.