Quantitative comparison of the mRNA expression for IL-1β, TNF-α, IL-4 and IL-6 in the PVN of ANG II-infused rats treated early (A, B, C and D) or late (E, F, G and H) with PVN microinjections of p44/42 MAPK siRNA, a scrambled siRNA, or vehicle. Untreated rats served as Control. Values are mean ± SEM (n = 6-8 for each group). *P< 0.05, vs. Control.