Table 1.
Characteristics of the 113 studied patients during ICU stay
| Characteristics of patient population | NI - (88) | NI + (25) | p |
|---|---|---|---|
| Age (years) |
55 (45–65) |
55 (47–59) |
0.34 |
| Sex (male/female) |
48/40 |
17/8 |
0.38 |
| SAPS II score at admission |
45 (31–55) |
50 (38–57) |
0.43 |
| Admission diagnosis, n (%) |
|
|
0.07 |
| Acute respiratory failure |
26 (30) |
5 (20) |
|
| Neurologic failure |
22 (25) |
5 (20) |
|
| Cardiovascular failure |
16 (18) |
3 (12) |
|
| Polytrauma |
10 (11) |
6 (24) |
|
| Post operative |
3 (3) |
5 (20) |
|
| Miscellaneous |
11 (13) |
1 (4) |
|
| Site of infection, n (%) |
|
|
|
| Bacteremia |
|
11 (44) |
|
| Pneumonia |
|
9 (36) |
|
| Catheter related infection |
|
2 (8) |
|
| Candidemia |
|
3 (12) |
|
| Delay of NI, days |
|
11 (8–14) |
|
| Number of days without antibiotics before NI |
|
5 (3.5-5.5) |
|
| Central venous catheter, n (%) |
60 (68) |
25 (100) |
0.005 |
| Duration of central venous catheter, days |
11 (8–17) |
22 (14–35) |
0.001 |
| MV, n (%) |
58 (66) |
24 (96) |
0.02 |
| Duration of MV, days |
10 (5–14) |
25 (15–33) |
0.0007 |
| Length of ICU stay, days | 12 (7–18) | 29 (22–39) | < 0.0001 |
Data are presented as n (%) and median values (lower and upper quartiles). NI: Nosocomial Infection. SAPS: Simplified Acute Physiologic Score. MV: mechanical ventilation. ICU: Intensive Care Unit.