Figure 3. Association of Borrelia 16S rRNA targets per 10,000 genome equivalents and clinical symptoms.

(A) Boxplot showing log₁₀ 16S copies determined for biopsy specimens from patients presenting with (+) or without (−) systemic symptoms. (B) Distribution of Borrelia 16S copies quantified from specimens taken from patients reporting a previous diagnosis of LD. (C) 16S copies quantified for biopsies taken from EM lesions with or without central clearing. Whiskers indicate the minimal and maximal copy number determined. Data were analyzed using the Mann–Whitney test.