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. 2013 May 16;8(5):e63613. doi: 10.1371/journal.pone.0063613

Figure 4. Effects of Dll4 on the expression of Jagged or Delta mRNA in ovalbumin-stimulated dendritic cells.

Figure 4

Dll4-pretreated or untreated immature DCs were or were not stimulated with ovalbumin (OVA). Additionally, under culture conditions of Dll4 (5 µg/mL) plus OVA-treated DCs, a blocking anti-Dll4 monoclonal antibody (25 µg/mL) was added until the end of culture. Cells were harvested after 5 h, and Jagged (Jgd)1, Jgd2, Dll1, and Dll4 mRNA accumulations were measured using a real-time RT-PCR. Data are the mean ± SEM and are representative of 3 independent experiments. * p<0.05, ** p<0.01 compared to OVA-treated DCs (OVA group). ## p<0.01 compared to OVA/Dll4 (5 µg) group.