Figure 8. Effects of later (12 hr) intra-BLA protein synthesis inhibition on behavioral and mPFC neuronal opiate memory consolidation.

Group CPP data showing that intra-BLA vehicle A , or anisomycin administration (C) at 12 hrs post-conditioning does not block subsequent behavioral recall of consolidated opiate reward memory. In addition, mPFC neuronal populations show robust, associative firing rate increases in response to morphine environment exposures during real-time CPP test recordings (panels B , D; raster samples taken from single rats showing mPFC neuronal firing recorded in real-time across saline or morphine-environmental exposure).