Table 1. Means of IFN-γ, IL-4 and IL-10 levels for ALL study volunteers (n = 22) from whole blood stimulation:
Antigenic stimulant IFN—γ pcm/ml IL-4 pcm/ml IL-10 pcm/ml |
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Control (No antigens/No peptides) 154 ± 222 (65) 16.5 ± 26.0 (4) 825 ± 580 (705) |
Soluble Leishmania antigen 177 ± 306 (68) 13.5 ± 30.0 (8) 827 ± 448 (832) |
P1 peptide 126 ± 209 (50) 17.7 ± 24.5 (8.5) 1223 ± 678(1287)* |
P2 peptide 120 ± 175 (53) 19.7 ± 25.9 (13) 940 ± 538 (763) |
P3 peptide 133 ± 213 (51) 19.4 ± 24.0 (9.5) 895 ± 508 (821) |
P4 peptide 165 ± 274 (71) 17.2 ± 22.4 (12) 544 ± 652 (217) |
P1, P2, P3 and P4 the predicted and synthesized peptides. Continuous variables are expressed as means ± SD (median). pcm/ml = picogram/ml. *p = 0.03