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. 2013 May 16;7(5):e2222. doi: 10.1371/journal.pntd.0002222

Figure 1. tpr alleles among treponemal species, subspecies and strains.

Figure 1

tprD2: A tprD allele which contains a 330-bp unique central region and three smaller heterogeneous regions at the 3′ end. tprC-like and tprD-like: similar to tprC or tprD, respectively, with small sequence differences in discrete variable regions (DVRs). tprGJ: A chimera where the 3′ end contains tprJ signatures. tprGI: A chimera where the 5′ end is homologous to tprG, and the central and 3′ regions are homologous to the corresponding regions of tprI. truncated: Predicted truncated proteins due to a frameshift. tprA-like, tprI-like and tprL-like contain small sequence differences. tprE-like and tprH-like contains small sequence differences that segregate syphilis from non-syphilis treponemes. tprL1: A unique tprL allele in T. p. pertenue and Fribourg-Blanc strain. * indicates that tprC and tprD in the Nichols strain and that tprI-like sequences in the tprF and tprI loci are also identical in the pertenue subspecies and the Fribourg-Blanc treponeme.