. Author manuscript; available in PMC: 2013 May 17.

Published in final edited form as: Am J Psychiatry. 2011 Jul 28;168(10):1075–1082. doi: 10.1176/appi.ajp.2011.10060853

TABLE 2.

Functional MRI Activation For Specified Regions of Interest in a Study of White Matter Hyperintensitites in Late-Life Depression^a

		Full Group			Depressed Patients > Nondepressed Comparison Subjects
Region	MNI Coordinates	t (df=59)^b	Cluster Size	P^c	t (df=58)^b	Cluster Size	p^c
Rostral cingulate	2, 26, −3	3.61	5	0.003	2.74	3	0.037
Amygdala	22, −4, −18; −22, −6, −18	6.90	138	0.004	2.71	1	0.087
Insula	−30, 20, −3; 36, 22, 8	4.70	361	0.001	—	—	—

Table includes all values that meet a threshold of p<0.1, corrected. MNI=Montreal Neurological Institute.

Maximum voxel-wise t score.

Small-volume correction using specified region of interest.