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. 2013 May 17;3:124. doi: 10.3389/fonc.2013.00124

Table 1.

Summary of PML modifications implicated in various human cancers.

Type of PML modification Cancer type PML gain (+) or loss(−) Reference Section in the text
Ubiquitination by E6AP B-cell lymphoma Wolyniec et al. (2012b) Section “Ubiquitination”
Phosphorylation by CK2 NSCL cancer Scaglioni et al. (2006) Section “Phosphorylation”
SUMOylation by PIAS1 NSCL cancer Rabellino et al. (2012) Section “SUMOylation”
Ubiquitination by KLHL20 Prostate cancer Yuan et al. (2011) Section “Ubiquitination”
Phosphorylation by ERK2/Pin1 Breast cancer Lim et al. (2011) Section “Phosphorylation”
Unknown mechanism Breast cancer + Carracedo et al. (2012) Section “Targeting GOF PML Activities in Non-Hematopoietic Malignancies”
Mutant p53 context Colon cancer + Haupt et al. (2009) Section “Targeting GOF PML Activities in Non-Hematopoietic malignancies”

Reference to the section in the text and to the original publication is listed.