Table 1.
Demographic and Characteristics for 198 Enrolled Patients
| Characteristic | No. (%) |
|---|---|
| Sex | |
| Male | 121 (61) |
| Female | 77 (39) |
| Race | |
| Caucasian | 161 (82) |
| African American | 15 (8) |
| Othera | 21 (10) |
| Ethnicity | |
| Hispanic | 19 (10) |
| Non-Hispanic | 177 (89) |
| Unknown | 2 (1) |
| Age, Median (IQR) | 7.8 (3.7–13.5) |
| HSCT, with underlying diagnosis | |
| Total | 169 (85) |
| HSCT for ALL | 36 (18) |
| HSCT for AML/MDS | 39 (20) |
| HSCT for solid tumor | 30 (15) |
| HSCT, otherb | 64 (32) |
| Chemotherapy, with underlying diagnosis | |
| Total | 29 (15) |
| ALL | 6 (3) |
| AML/MDS | 17 (9) |
| Solid tumor | 6 (3) |
| Duration neutropeniac | |
| Mean | 24.8 |
| Median | 20 |
| Range | 3–343 |
| Antifungal prophylaxisc | |
| Any prophylaxis | 185 |
| Fluconazole | 143 (77) |
| Voriconazole | 15 (8) |
| Caspofungin | 7 (4) |
| Amphotericin product | 20 (11) |
| Chemotherapy contained steroid exposured | 65 (37) |
| TBI exposuree | 83 (47) |
Abbreviations: ALL, acute lymphoblastic leukemia; AML/MDS, acute myeloid leukemia/ myelodysplastic syndrome; HSCT, hematopoietic stem cell transplant; IQR, interquartile range; TBI, traumatic brain injury.
aIncludes Asian (n = 4), Native American (n = 6), Pacific Islander (n = 2), other (n = 7), and unknown (n = 2).
bThe most common other diagnoses included severe aplastic anemia (n = 11), chronic myelogenous leukemia (n = 7), Hodgkin's lymphoma (n = 7), Wiskott-Aldrich syndrome (n = 4), Fanconi anemia (n = 4).
cData available for 185 of the 198 enrolled patients.
dData available for 178 of the 198 enrolled patients.
eData available for 176 of the 198 enrolled patients.