Table 2.

Performance Characteristics of Serum and Urine Galactomannan Enzyme Immunoassay Test, Requiring Confirmation^a

Performance Characteristic		Sensitivity, %	Specificity, %	PPV, %	NPV, %	False-Positive Rate, %
Serum GM (threshold 0.5)	Probable IAb	0	95	0	99	5.2
	Possible and Probable IA	13	96	30	89	4.1
Serum GM (threshold 1.0)	Probable IAb	0	96	0	99	3.6
	Possible and Probable IA	13	98	43	89	2.3
Urine GM (threshold 0.5)	Probable IAb	100	80	2.7	100	20.2
	Possible and Probable IA	19	79	11	88	20.9
Urine GM (threshold 1.0)	Probable IAb	100	83	3.2	100	16.9
	Possible and Probable IA	14	82	9.6	88	17.7

Abbreviations: GM, galactomannan; IA, invasive aspergillosis; NPV, negative predictive value; PPV, positive predictive value.

^aA specimen was considered positive if the test result exceeded the indicated threshold, in duplicate.

^bCalculated using one case meeting criteria for probable IA.