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Morphology of the myofibroblast. (A, B) Cartoons depicting the morphology and cytoskeletal components of a fibroblast (A) versus a myofibroblast (B). For more detail, see text. (C, D) Immunofluorescence images showing the stress fiber organization (red-phalloidin staining) and focal adhesion proteins (A, green-Hic-5 immunostaining; B, green-vinculin immunostaining) of a myofibroblast on a glass coverslip (C) or in a collagen gel (D). Scale bars: (C) 50 μm; (D) 40 μm.
