Table 1.
Active | Placebo | P-Value1 | |||
---|---|---|---|---|---|
N=3778 | % | N=3867 | % | ||
Age group at screening | 0.88 | ||||
50–59 | 1223 | 32.4 | 1232 | 31.9 | |
60–69 | 1740 | 46.1 | 1799 | 46.5 | |
70–79 | 815 | 21.6 | 836 | 21.6 | |
| |||||
Race/ethnicity | 0.27 | ||||
White | 2945 | 78.0 | 3001 | 77.6 | |
Black | 514 | 13.6 | 565 | 14.6 | |
Hispanic | 189 | 5.0 | 181 | 4.7 | |
American Indian | 31 | 0.8 | 18 | 0.5 | |
Asian/Pacific Islander | 54 | 1.4 | 49 | 1.3 | |
Unknown | 45 | 1.2 | 53 | 1.4 | |
| |||||
HRT use status | 0.43 | ||||
Never used | 1929 | 51.1 | 1916 | 49.6 | |
Past user | 1304 | 34.5 | 1373 | 35.5 | |
Current user | 544 | 14.4 | 575 | 14.9 | |
| |||||
HT Duration | 0.52 | ||||
< 5 years | 960 | 51.9 | 1036 | 53.1 | |
5 – 10 years | 348 | 18.8 | 377 | 19.3 | |
≥ 10 years | 541 | 29.3 | 538 | 27.6 | |
| |||||
Body-mass index (kg/m2), baseline | 0.21 | ||||
< 25 | 785 | 20.9 | 771 | 20.1 | |
25 – < 30 | 1289 | 34.3 | 1391 | 36.2 | |
≥ 30 | 1687 | 44.9 | 1683 | 43.8 | |
| |||||
Smoking status | 0.30 | ||||
Never | 1988 | 53.1 | 1972 | 51.5 | |
Past | 1417 | 37.9 | 1489 | 38.9 | |
Current | 336 | 9.0 | 370 | 9.7 | |
| |||||
Parity | 0.04 | ||||
Never pregnant/Never had term pregnancy | 350 | 9.3 | 307 | 8.0 | |
≥1 term pregnancy | 3400 | 90.7 | 3539 | 92.0 | |
| |||||
Age at first birth, y | 0.53 | ||||
<20 | 822 | 27.0 | 872 | 27.3 | |
20 – 29 | 2060 | 67.7 | 2128 | 66.7 | |
30+ | 163 | 5.4 | 190 | 6.0 | |
| |||||
Hysterectomy age group | 0.17 | ||||
<40 | 1495 | 39.8 | 1501 | 39.0 | |
40–49 | 1643 | 43.7 | 1662 | 43.2 | |
50–54 | 345 | 9.2 | 412 | 10.7 | |
55+ | 275 | 7.3 | 271 | 7.0 | |
| |||||
Bilateral oophorectomy | 1370 | 39.0 | 1507 | 41.8 | 0.01 |
| |||||
Treated diabetes (pills or shots) | 243 | 6.4 | 250 | 6.5 | 0.95 |
| |||||
Hypertensive (Self-report or high BP) | 1806 | 51.1 | 1844 | 51.2 | 0.92 |
| |||||
History of high cholesterol requiring pills | 490 | 14.3 | 536 | 15.5 | 0.16 |
| |||||
Statin group | 288 | 7.6 | 302 | 7.8 | 0.76 |
| |||||
Aspirin use >=80 mg for at least 30 days | 712 | 18.8 | 784 | 20.3 | 0.12 |
| |||||
History of angina | 243 | 6.5 | 253 | 6.6 | 0.82 |
| |||||
History of CABG/PTCA | 69 | 1.9 | 70 | 1.8 | 0.96 |
| |||||
Stroke ever | 51 | 1.3 | 47 | 1.2 | 0.60 |
| |||||
History of DVT or PE | 65 | 1.7 | 60 | 1.6 | 0.56 |
| |||||
History of fracture age 55+ | 455 | 16.5 | 447 | 15.8 | 0.51 |
| |||||
Times fell down last 12 months | 0.16 | ||||
None | 2368 | 67.5 | 2331 | 65.2 | |
1 time | 680 | 19.4 | 722 | 20.2 | |
2 times | 296 | 8.4 | 346 | 9.7 | |
3 or more times | 164 | 4.7 | 174 | 4.9 |
Test of association.