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. 2013 May 1;3(5):917–926. doi: 10.1534/g3.113.005561

Table 2. Genes in the screen.

Gene Name Short Description Degree of Suppression
BAP2 High-affinity branched aminoacid permease Strong
ECO1 Acetyltransferase required for Smc3p acetylation during the establishment of sister chromatid cohesion Strong
HTB1 Histone H2B Strong
CDC34 Ubiquitin-conjugating enzyme (E2) and catalytic subunit of SCF ubiquitin-protein ligase complex Strong
CHD1 Chromatin remodeller Strong
CRM1 Major karyopherin, involved in export of proteins, RNAs, and ribosomal subunits from the nucleus Strong
MOB1 Component of the mitotic exit network Strong
DDC1 Member of the 9-1-1 clamp essential for the DNA damage response Strong
CST6 Basic leucine zipper (bZIP) transcription factor Strong
MPH1 Helicase that functions in an error-free DNA damage bypass pathway Strong
YKL044w Gene of unknown function Strong
SIS2 Negative regulatory subunit of the protein phosphatase 1 Ppz1 Strong
UBC11 Ubiquitin-conjugating enzyme Strong
NHP6A High-mobility group non-histone chromatin protein Strong
TPT1 tRNA 2’-phosphotransferase, catalyzes the final step in yeast tRNA splicing Strong
TAF3 TFIID subunit involved in transcription initiation Strong
RTT103 Involved in transcription termination Medium
SRL3 Cytoplasmic protein that, when overexpressed, suppresses the lethality of a rad53 null mutation Medium
RTT109 Histone H3 acetylase Medium
GID8 Member of a ubiquitin ligase that carries out poly-ubiquitination. Medium
GIS2 Protein with seven cysteine-rich CCHC zinc-finger motifs Medium
RTT106 Histone chaperone Medium
YOL114c Gene of unknown function Medium
IRC13 Null mutant displays increased levels of spontaneous Rad52 foci Medium
NUP1 Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs Weak
PPS1 Protein phosphatase with specificity for serine, threonine, and tyrosine Weak
UBP14 Ubiquitin-specific protease Weak
NSE3 Essential subunit of the Mms21-Smc5-Smc6 complex Weak
PAB1 Poly(A) binding protein, part of the 3′-end RNA-processing complex Weak
DAM1 Essential subunit of the Dam1 complex, involved in kinetochore movement Weak
CPD1 Cyclic nucleotide phosphodiesterase Weak
UBP7 Ubiquitin-specific protease that cleaves ubiquitin-protein fusions Weak
RPB4 Subunit of RNA polymerase involved in 3′-end RNA processing and export Weak
RFX1 Major transcriptional repressor of DNA-damage-regulated genes Weak
HAS1 ATP-dependent RNA helicase, localizes to nuclear pore Weak
CNM67 Component of the spindle pole body outer plaque Weak