Multisite
intracerebral microdialysis. Schematic representation of the simultaneous
implantation of four dialysis probes in the prefrontal cortex (PFC),
striatum (STR), substantia nigra pars reticulata (SNr), and hippocampus
(HIPP) on the ipsilateral DA-depleted side. Dialysis probes were implanted
in isoflurane-anesthetized rats 3 weeks after the injection of 6-hydroxydopamine
(6-OHDA) in the right medial forebrain bundle (MFB). One stereotaxic
arm holds two dialysis probes for the STR and HIPP (4 mm long) and
another holds two dialysis probes for the PFC (4 mm long) and SNr
(2 mm long). The stereotaxic coordinates (in mm) were as follows:
PFC, anteroposteriority from bregma (AP) = 3.00, laterality (L) =
0.4, ventrality (V) = 4; STR, AP = 1.20, L = 3, V = 2.4; SNr, AP = −5.30,
L = 2.2, V = 1.2; HIPP, AP = −5.80, L = 5, V = 2.4. AP coordinates
from bregma are indicated in italics.