Figure 2.

Inhibitory effect of FBN on A-431 cell growth.

Notes: Cells were treated with increasing concentrations of flurbiprofen, NO flurbiprofen, and FBN for 24 hours. Cell viability was determined by MTT assay as described in the Materials and methods section. Results are means ± SEM of three different experiments performed in triplicate. *P < 0.05 compared to flurbiprofen; ^†P < 0.01 compared to flurbiprofen; ^§P < 0.05 compared to NO-flurbiprofen.

Abbreviations: FBN, flurbiprofen benzyl nitrate; IC₅₀, half maximal inhibitory concentration; NO, nitric oxide; NSAID, nonsteroidal anti-inflammatory drug; SEM, standard error of the mean.