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. 2013 May 17;8(5):e64051. doi: 10.1371/journal.pone.0064051

Figure 8. ABT-263 increases BAX activation during metformin and 2DG treatment.

Figure 8

Activation of pro-apoptotic BAX in KNS42 cells was assessed via immunostaining using an antibody specific to active BAX after 8 hours of treatment with each agent or the various combinations. Representative images are shown from at least three independent experiments.