Table 1. Effects of various growth factors on cancer cell morphology.
Growth Factor | OCUM-2MD3 | OCUM-12 | OCUM-2M | |||
concentration | concentration | concentration | ||||
10 ng/ml | 100 ng/ml | 10 ng/ml | 100 ng/ml | 10 ng/ml | 100 ng/ml | |
TGFβ1 | + | + | + | + | − | − |
HGF | − | + | − | + | − | − |
FGF2 | − | − | − | − | − | − |
FGF7 | − | − | − | − | − | − |
EGF | − | − | − | − | − | − |
IGF1 | − | − | − | − | − | − |
VEGF | − | − | − | − | − | − |
PDGF-BB | − | − | − | − | − | − |
+; Positive morphologic changes, −; No changes.
The culture medium was consisted of DMEM with 10% FBS.