Figure 1. Experimental paradigm.

Panel A indicated that acupuncture stimulation was performed at acupoint ST36 on the right leg (Zusanli, arrow pointing to dark pink dot). Panel B indicated that needling was performed at a nearby nonacupoint on the right leg (NAP, arrow pointing to dark cyan dot). The red line refers to needle administration, and the green line represents no acupuncture manipulation with needle inserted, the blue line indicates a 6-minute resting state or post-acupuncture resting state.