Table 3. The functional connectivity between the DMN key nodes and their alterations induced by acupuncture within the delta band (0.5–4 Hz).
Functional Connectivity | Delta | |||||
Rest | NAP | P-value | ST36 | P-value | ||
MFG-SFG | 0.3643 | 0.4011 | 0.358 | 0.4299 | 0.723 | |
SFG-ACC | 0.2332 | 0.3016 | 0.231 | 0.1383 | 0.407 | |
ACC-PCC | 0.0546 | 0 | – | 0.0779 | 0.611 | |
PCC-STG | 0.0551 | 0.0710 | 0.841 | 0.0709 | 0.019 | |
STG-AG | 0 | 0 | – | 0 | – | |
AG-IPL | 0.6478 | 0.6209 | 0.635 | 0.6226 | 0.075 | |
IPL-MTG | 0.1289 | 0.1276 | 0.839 | 0.1199 | 0.699 | |
MTG-MFG | 0.0447 | 0.0817 | 0.125 | 0 | – | |
MFG-ACC | 0.6874 | 0.7952 | 0.575 | 0.6373 | 0.193 | |
SFG-PCC | 0.1176 | 0.0954 | 0.119 | 0.0953 | 0.623 | |
ACC-STG | 0.0823 | 0.0818 | 0.774 | 0.1167 | 0.053 | |
PCC-AG | 0.2077 | 0.2081 | 0.831 | 0.2145 | 0.752 | |
STG-IPL | 0.0504 | 0 | – | 0 | – | |
AG-MTG | 0.2146 | 0.2176 | 0.856 | 0.2438 | 0.648 | |
IPL-MFG | 0.0420 | 0.0632 | 0.742 | 0 | – | |
MTG-SFG | 0.0670 | 0.0806 | 0.248 | 0.0631 | 0.617 | |
MFG-PCC | 0 | 0 | – | 0 | – | |
SFG-STG | 0.0477 | 0 | – | 0.0975 | 0.161 | |
ACC-AG | 0.0516 | 0 | – | 0 | – | |
PCC-IPL | 0.2443 | 0.2363 | 0.684 | 0.2482 | 0.742 | |
STG-MTG | 0.2273 | 0.2622 | 0.396 | 0.2133 | 0.869 | |
AG-MFG | 0 | 0 | – | 0 | – | |
IPL-SFG | 0 | 0 | – | 0 | – | |
MTG-ACC | 0 | 0 | – | 0 | – | |
MFG-STG | 0.0755 | 0.0867 | 0.636 | 0.1219 | 0.195 | |
SFG-AG | 0 | 0 | – | 0.0475 | – | |
ACC-IPL | 0.1461 | 0.1228 | 0.395 | 0.1492 | 0.953 | |
PCC-MTG | 0.0685 | 0.0504 | 0.938 | 0.0843 | 0.872 |
The maximum of the 4 pairwise connections obtained between the two ROIs located in both hemispheres was defined as the connectivity between the two nodes (one sample t-test, P<0.05). Significant alterations induced by acupuncture at ST36 relative to NAP were based on the paired t-test (P<0.05) or with the emergence/suspension of functional connectivity following acupuncture compared with the resting state.